Resistome profiling poses several advantages over PCR or qPCR alone. No prior knowledge of the ARGs of interest is needed in resistome profiling as all the sequences are being compared to curated and updated reference databases. This comparison enables the simultaneous and global characterization of the potential ARGs present in the microbiome of interest. The ARG sequence(s) of interest can be identified, extracted and used for further analyses including phylogenetic and evolutionary analyses. Identification of ARGs sequences of interest also enables the identification of potential putative host(s), and in some cases, the mobile genetic origin (i.e. plasmid-, transposon and/or phage-related). 

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